Paper Title:
Ultrafine Grinding of Radix Salvia Miltiorrhiza Particles and the Physicochemical Properties by High Speed Centrifugal Sheering
  Abstract

Radix salvia miltiorrhiza is a commonly used herbal medicine in China, and tanshinone IIA is one of the major active ingredients. Nano Radix salvia miltiorrhiza particles were successfully prepared by high speed centrifugal sheering (HSCS) technology, and the prepared nanoparticles suspension was subsequently spray-dried. The different properties of nano particles and raw powder were systematically studied by laser light scattering granulometric analyzer, TEM, SEM and FTIR. The extractive quantity of tanshinone IIA was determined by high-performance liquid chromatography (HPLC). The results illustrate that raw Radix salvia miltiorrhiza powder can be ultrafinely ground to nanosize within 50min, and the molecular structure of active ingredients doesn’t change after being ground. Furthermore, the active ingredients can dissolve out directly and fully, and the extractive ratio of tanshinone IIA increases 28.6% by HSCS processing. It is valuable to combine nanotechnology and TCM to improve the bioavailability and rapid releasing.

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
215-218
DOI
10.4028/www.scientific.net/KEM.330-332.215
Citation
Y.L. Su, Z. Y. Fu, W. M. Wang, H. Wang, Y. C. Wang, J. Y. Zhang, P.Y. Ma, "Ultrafine Grinding of Radix Salvia Miltiorrhiza Particles and the Physicochemical Properties by High Speed Centrifugal Sheering", Key Engineering Materials, Vols. 330-332, pp. 215-218, 2007
Online since
February 2007
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$32.00
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