Comparison of Biomineralization on Calcium Phosphate Implants in Rabbit and Dog Models |
| Journal |
Key Engineering Materials (Volumes 330 - 332) |
| Volume |
Bioceramics 19 |
| Edited by |
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu |
| Pages |
27-30 |
| DOI |
10.4028/www.scientific.net/KEM.330-332.27 |
| Online since |
February, 2007 |
| Authors |
Ren Long Xin,
Yang Leng,
Ji Yong Chen,
Xiu Dong Yang
|
| Keywords |
Bioceramic, Biomineralization, Calcium Phosphate (CaP), Transmission Electron Microscopy (TEM) |
| Abstract |
Porous alpha- tricalcium phosphate (α-TCP) was implanted in rabbit and dog models to
investigate its induction of calcium phosphate (Ca-P) formation. The morphology and structure of
the formed Ca-Ps were examined using scanning electron microscopy (SEM) and transmission
electron microscopy (TEM), respectively. The results showed an animal-dependent behavior of in
vivo Ca-P formation. There were flake-like octacalcium phosphate (OCP) precipitates in the rabbit
but rod-like hydroxyapatite (HA) precipitates in the dog model. In addition, high-resolution TEM
(HRTEM) image revealed that there was OCP structure in certain portions of the rod-like HA
precipitates in the dog model. And the orientation relation of OCP/HA was deduced as OCP
(010)//HA (0 10) and OCP (001)//HA (00 1) . This implied that the in vivo HA was formed via
OCP precursor phase. |
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