Paper Title:
Ce(IV) Doped TiO2 Nanoparticles and the Effect on Proliferation of BEL7402 Human Hepatoma Cells
  Abstract

To investigate nanoparticles’ antitumor effect, a globose 30~35nm Ce(IV) doped Titanium dioxide nanoparticles (CDT) were prepared by impregnation method and characterized by X-ray diffraction (XRD) and transmission electron microscopy(TEM). Proliferation of BEL7402 human Hepatoma cells was studied in vitro by using fluorescence microscopy and Flow Cytometry. The results show that cerium elements doping enhanced thermal stability of nano-size titanium dioxide to 800°C. With UV irradiated for 8min, BEL7402 were induced a dose-dependent apoptosis by CDT, about 28.2% , 41.5% and 88.3% cells were induced apoptosis after 24h at concentration of 60, 120 and 180ug/ml respectively, relative to 3.9% of that of control group cell just only in the presence of UV.

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
307-310
DOI
10.4028/www.scientific.net/KEM.330-332.307
Citation
L. Wang, J. Mao, X.L. Zhang, M.J. Tu, B. Kan, Y.Q. Wei, "Ce(IV) Doped TiO2 Nanoparticles and the Effect on Proliferation of BEL7402 Human Hepatoma Cells", Key Engineering Materials, Vols. 330-332, pp. 307-310, 2007
Online since
February 2007
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Price
$32.00
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