Paper Title:
Development of Poly(Vinyl Alcohol)-Collagen-Hydroxyapatite Nanohybrids for Tissue Grafting
  Abstract

Poly(vinyl alcohol) (PVA) was introduced during in situ synthesis of hydroxyapatite (HA) in neutral collagen (COL) solution and final PVA-COL-HA nanohybrids were achieved via sequential steps including gelation by fibrillogenesis, freezing-thawing physical crosslinking, removal of unreacted residues and dehydration. This method is expected to endow the pure PVA with good bioactivity and meanwhile the presence of elastic PVA would improve the properties of COL-HA composites. The phase, microstructure and possible molecular interactions of the achieved PVA-COL-HA nanohybrids were analyzed by using X-ray diffraction, Fourier transform infra-red spectroscopy and scanning electron microscopy. The results indicate that the inorganic phase is poorly crystallized apatite with a nanometer size due to the confinement of organic macromolecules which forms a network structure.

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
329-332
DOI
10.4028/www.scientific.net/KEM.330-332.329
Citation
X. M. Wang, X. D. Li, G. Q. Zheng, X. L. Wang, X. D. Zhang, Z. W. Gu, "Development of Poly(Vinyl Alcohol)-Collagen-Hydroxyapatite Nanohybrids for Tissue Grafting", Key Engineering Materials, Vols. 330-332, pp. 329-332, 2007
Online since
February 2007
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Price
$32.00
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