Paper Title:
Bioactive Hydroxyapatite/ Polyvinyl Alcohol Composite for Repair and Regeneration of Articular Cartilage
  Abstract

In this work, a new kind of bioactive PVA/HA hydrogels use as artificial cartilage were prepared by in situ sol-gel synthesis method. Simulated experiments were performed to evaluate and compare the bioactive ability and properties of the hydrogels in simulated body solution. PVA/HA Cartilage implants were developed and used to repair articular cartilage defect in rabbit knee. The macroscopic and histological observation of animal experiments displayed that the implanted hydrogels combined tightly to ambient tissues, and some bone-like tissue grew into the bottom of the implants from the base-bone to form more deep-set binding.

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
475-478
DOI
10.4028/www.scientific.net/KEM.330-332.475
Citation
Y. D. Zheng, Y. J. Wang, X. F. Chen, H. D. Lu, Q. Liu, "Bioactive Hydroxyapatite/ Polyvinyl Alcohol Composite for Repair and Regeneration of Articular Cartilage", Key Engineering Materials, Vols. 330-332, pp. 475-478, 2007
Online since
February 2007
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Price
$32.00
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