Paper Title:
A Novel Way of Dispersing Fine Ceramic Particles in PLGA Matrix
  Abstract

α-tricalcium phosphate (α-TCP) was prepared by a wet precipitation reaction between calcium hydroxide and orthophosphoric acid solutions. The as-synthesised powder was then characterised using a Scanning Electron Microscope (SEM) equipped with Energy Dispersive Spectroscope (EDS), X-ray Diffraction (XRD) and Fourier Transform Infrared Spectroscope (FTIR). Analyses revealed that a phase-pure powder with a Ca/P ratio of 1.5 was produced. In addition, nanosized α-TCP particles of diameter ~ 70 nm were agglomerated to form larger particles of 10μm in diameter. It was found that by the combination of attritor milling and solution evaporation, the agglomerates of α-TCP nanoparticles could be broken down, and distributed evenly within the poly(D,L-lactic-co-glycolic acid) (PLGA) matrix. Thus, a α-TCP/PLGA nanocomposite was successfully produced by a modified solution evaporation method at room temperature followed by hot pressing at 150 °C. The achievable ceramic loading was approximately 38 wt.%, which was confirmed by thermal gravimetric analysis (TGA).

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
511-514
DOI
10.4028/www.scientific.net/KEM.330-332.511
Citation
Z. Yang, E.S. Thian, S. Best, R. Cameron, "A Novel Way of Dispersing Fine Ceramic Particles in PLGA Matrix", Key Engineering Materials, Vols. 330-332, pp. 511-514, 2007
Online since
February 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: M. Yusop, De Liang Zhang, M. Wilson
Abstract:Alumina-iron nanocomposite powders containing 5vol.% of iron were fabricated by high-energy ball milling with different ball-to-powder...
131
Authors: Taha Rostamzadeh, H. Shahverdi, R. Sarraf-Mamoory, A. Shanaghi
Abstract:Mechanical alloying is one of the most successful methods for the manufacturing of metal matrix nanocomposite powders. In this study, Al/SiC...
764
Authors: Ehsan Taheri Nassaj, Ali Alizadeh
Chapter 9: Composite Materials II
Abstract:Mechanical milling was used to synthesize Al nanostructured powder in a planetary ball-mill under argon atmosphere up to 20 h. The same...
2733
Authors: Saeed Sheibani, Abolghasem Ataie, Saeed Heshmati-Manesh, Alfonso Caballero Martínez
Abstract:In this research, formation mechanism of a Cu/10 wt.% Cr-10 wt.% Al2O3 nanocomposite via mechanical alloying and...
7
Authors: Mariano Casas Luna, Edgar Benjamin Montúfar, Miroslava Horynová, Pavel Gejdoš, Lenka Klakurková, Sebastián Díaz de la Torre, Jozef Kaiser, Ladislav Čelko
Chapter 7: Surface and Interface Microstructure and Properties
Abstract:The fabrication of a composite material based on magnesium (Mg) and tricalcium phosphate is reported in this work. Rods of β-tricalcium...
412