Paper Title:

Collagenous Molecule Immobilization on Hydroxyapatite Surface

Periodical Key Engineering Materials (Volumes 330 - 332)
Main Theme Bioceramics 19
Edited by Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages 741-744
DOI 10.4028/
Citation Bo Jiang et al., 2007, Key Engineering Materials, 330-332, 741
Online since February 2007
Authors Bo Jiang, Zhi Hong Wu, Jing Ying Zeng, Jian Lu, Qing Rong Wei, Xing Dong Zhang, Zhong Wei Gu
Keywords Collagen, Hydroxyapatite (HAP), Immobilisation, Suface Modification, γ-Ray
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Collagenous molecule was successfully immobilized to hydroxyapatite (HA) surface through a molecular bridge (2-Hydroxyethyl acrylate, HEMA) that was grafted to the surface with covalent bond by gamma irradiation. Hydroxyapatite modified by atelocollagen had been characterized by several surface sensitive techniques, such as FT-IR, SEM, XPS. The investigations showed that the collagen, a bioactive macromolecule, was immobilized on the HA surface through covalent bond.