Paper Title:
Comparing Adsorptive Property of Natural and Synthesized Hydroxyapatite to Albumin, Fibrinogen and IgG
  Abstract

The aim of this study was to compare the plasma protein adsorptive property of the natural hydroxyapatite (HA) and the synthesized HA to human albumin (Alb), fibrinogen (Fib) and immunoglobulin G (IgG). Different methods such as reflectometry interference spectroscopy (RIfS) measuring, Fourier transform infrared spectroscopy (FTIR) analysis and weighing assessment were used to measure the adsorbed amount of Alb, Fib and IgG on the natural HA and the synthesized HA. To compare the adsorptive property of protein adsorbed on these two kinds of materials, the ratio of Alb/Fib (RA/F) and the ratio of Alb/IgG (RA/I) were calculated. The results from all three methods showed that the values of RA/F and RA/I obtained with natural HA were smaller than those obtained with synthesized HA, that indicated that the natural HA adsorbed more human fibrinogen than human albumin and thas it would enhance blood coagulation and in favor of bone repairing.

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
869-872
DOI
10.4028/www.scientific.net/KEM.330-332.869
Citation
X. Y. Lü, H. Yan, B. Z. Zheng, A. P. Wu, "Comparing Adsorptive Property of Natural and Synthesized Hydroxyapatite to Albumin, Fibrinogen and IgG", Key Engineering Materials, Vols. 330-332, pp. 869-872, 2007
Online since
February 2007
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