Paper Title:
Studies on Characteristics and Adsorption of BSA on Hydrogel Biomaterials
  Abstract

Hydrogel biomaterials were synthesized by radical copolymerization of N-vinyl pyrrolidone (NVP) and 2-hydroxyethylmathacrylate (HEMA), with azobisisobutyronitrile (AIBN) as an initiator, reacting at 60~70°C for 24 hours, which were designed as contact lens due to the good chemical stability and high biocompatibility. The absorbency of bovine serum albumin (BSA) was measured by the ultraviolet spectrophotometer. The influence of pH, initial protein concentration and ionic strength were investigated in detail. The results showed that the absorption of protein on hydrogel biomaterials increased with the immersing time increasing, and was stable during 4 days. The absorption of protein on hydrogel increased with the equilibrium water content increasing. The protein absorption on hydrogels reduced the permeability of the oxygen of the biomaterials.

  Info
Periodical
Key Engineering Materials (Volumes 330-332)
Main Theme
Edited by
Xingdong Zhang, Xudong Li, Hongsong Fan, Xuanyong Liu
Pages
901-904
DOI
10.4028/www.scientific.net/KEM.330-332.901
Citation
G.X. Tan, Y. D. Cui, Y. J. Wang, "Studies on Characteristics and Adsorption of BSA on Hydrogel Biomaterials", Key Engineering Materials, Vols. 330-332, pp. 901-904, 2007
Online since
February 2007
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Price
$32.00
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