Water-soluble binder based injection molding of submicrometer-sized and stabilized zirconia was reported in this paper. The binder phase is chosen as the mixtures of polyethylene glycol, high-density polyethylene, polyvinyl butyral and stearic acid. Binder removal is accomplished by a two-steped process. The water-soluble constituent is firstly removed by dissolution in the water and the remaining is removed through the followed thermal treatment. The apparent viscosities of different kinds of feedstock were tested. The influences of water-leaching time and temperature on the efficiency of PEG removal were discussed.