The machinable fluorophlogopite was drilled with tungsten-cobalt carbide and high-speed steel drill bits, respectively. The wear widths of major flank were measured, and the wear characteristic of twist was analyzed during drilling fluorophlogopite ceramics.Drilling experiments were carried to consider influence factors of drill bit wear, such as tool materials, cooling condition, spindle speed and tool angles. Tool materials and cooling conditions are the major factors to affect wear of drill bits. High-speed steel drill bits are not suitable for drilling fluorophlogopite ceramics. Cooling condition affects wear remarkably. With the rising of spindle speed, the wear widths of major flank grows. But apex angle has little affects on the tool wear rate. Research results indicate that low tool wear can be obtain through optimizing tool material and machining parameters in drilling fluorophlogopite ceramics.