Paper Title:
Application of Multilayer Collagen/HA Scaffold in Cartilage Tissue Engineering
  Abstract

In this article, a multilayer tissue engineering scaffold has been fabricated. The uppermost layer is consisted by the collagen and the downmost layer is consisted by the collagen/hydroxyapatide. Between the two layers, there have several continues changed collagen/HA layers at different ratio. These gradient scaffolds have been made by the freeze dried method. The morphology of the multiphase scaffold has been observed by the SEM. The chondrocytes from New Zealand rabbit knee joint were separated, harvested and cultured on the top layer of the scaffold. The histological and the immunohistochemical testing show that the chondrocytes keep its normal type in the 2 culture weeks.

  Info
Periodical
Key Engineering Materials (Volumes 336-338)
Edited by
Wei Pan and Jianghong Gong
Pages
1549-1552
DOI
10.4028/www.scientific.net/KEM.336-338.1549
Citation
G. Wu, Y. J. Wang, H. D. Lu, X. F. Chen, J. D. Ye, C. Y. Ning, N. R. Zhao, "Application of Multilayer Collagen/HA Scaffold in Cartilage Tissue Engineering", Key Engineering Materials, Vols. 336-338, pp. 1549-1552, 2007
Online since
April 2007
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Price
$32.00
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