Paper Title:
In Vivo Behavior of Injectable Fast-Setting Calcium Phosphate Cement
  Abstract

The in vivo study was performed to evaluate the biocompatibility and osteogenous ability of injectable fast-setting calcium phosphate cement (CPC). Eighteen four-week-old New Zealand white rabbits were divided into six groups randomly, three in each group. According to the principle of selfcontrast at the same time, cavities of 5mm in diameter and 6mm in depth were drilled in femoral condyle of rabbits. The materials were implanted into cavities of the left leg, the right leg as the blank control group. Rabbits were sacrificed at 2, 4, 8, 12, 16 and 24 weeks after surgery. The microstructure of specimens was observed using ESEM. The results showed that injectable fast-setting CPC had good fluidity and plasticity; it could be injected into bone defects and fast-set in situ. The start setting time was 5-8 min and the compressive strength was 25-30 MPa. The CPC had good biocompatibility and osteoconductivity, and benefited to the repair of bone defects.

  Info
Periodical
Key Engineering Materials (Volumes 336-338)
Edited by
Wei Pan and Jianghong Gong
Pages
1625-1627
DOI
10.4028/www.scientific.net/KEM.336-338.1625
Citation
L. M. Dong, C. Wang, R. Liu, J. M. Tian, Q. F. Zan, "In Vivo Behavior of Injectable Fast-Setting Calcium Phosphate Cement", Key Engineering Materials, Vols. 336-338, pp. 1625-1627, 2007
Online since
April 2007
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Price
$32.00
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