Paper Title:
Reconstruction of Kidney-Like Tissue Using ECM Gel and Rat Embryonic Kidney Fragments
  Abstract

Organ engineering remains a challenge to researchers. We tried to reconstruct kidney-like tissue using tissue engineering technique. Kidney fragments were isolated from rat E16 embryonic kidneys and seeded on either ECM gel or on polyglycolic acid (PGA) fibers, then implanted in vivo into the subcutaneous tissue of nude mice for 2 and 3 weeks, respectively. As a negative control, ECM alone was implanted. Results showed that kidney like tissue could be formed in ECMfragment constructs after 2 or 3 weeks of implantation, including the formation of glomeruli, tubules and collecting ducts. In addition, these structures seemed more mature in 3 weeks specimens than that of 2 weeks. Further development of this model may lay a solid foundation for kidney tissue engineering.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
1-4
DOI
10.4028/www.scientific.net/KEM.342-343.1
Citation
Y. J. Zhu, W. Liu, W. J. Zhang, G. D. Zhou, G. H. Liu, Y. L. Cao, "Reconstruction of Kidney-Like Tissue Using ECM Gel and Rat Embryonic Kidney Fragments", Key Engineering Materials, Vols. 342-343, pp. 1-4, 2007
Online since
July 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: S.B. Cho, Sang Bae Kim, Keon Joon Cho, Y.J. Kim, Tae Hee Lee, Y. Hwang
93
Authors: Shula Radin, V. Antoci, N. Hickok, Christopher S. Adams, Javad Parvizi, I.M. Shapiro, Paul Ducheyne
Abstract:Beneficial properties of room temperature processed silica sol-gels as resorbable and biocompatible materials for the controlled release of...
1323
Authors: Nuttapon Vachiraroj, Siriporn Damrongsakkul, Sorada Kanokpanont
Abstract:In this work, we developed a 3-dimensional bone tissue engineering scaffold from type B gelatin and hydroxyapatite. Two types of scaffolds,...
121
Authors: J. Mahadlek, J. Charoenteeraboon, Supab Choopun, Thawatchai Phaechamud
Abstract:Periodontal disease is a major cause of tooth loss, therefore a more recent approach such as thermosensitive gel is loaded with antimicrobial...
479
Authors: Zhen Gao, Xiao Ting Luo, Nian Sheng Li, Wei Deng, Shu Mei Li
Chapter 1: Material Engineering and its Application
Abstract:Objective: To evaluate the peripheral nerve regeneration using a nerve conduit of amniotic extracellular matrix (AECM). Methods: 5 mm gap in...
173