Paper Title:
In Vitro Studies of Macrophage Biological Behavior on Cardiovascular Biomaterials
  Abstract

Macrophages play a critical role in inflammatory response to implanted biomaterials and formation of restenosis. Macrophage adhesion may lead to macrophage activation and smooth muscle cell proliferation. Titanium oxide films on stainless steel are potential biomaterials for application to vascular stents. They have different influences on smooth muscle cell proliferation in in vivo tests, which could be the main reason for restenosis, but the mechanism is not clear. In this study we show that titanium oxide films can reduce inflammatory reaction with macrophages. Unstimulated macrophages release small amounts of chemical substance such as NO and give slight effect on smooth muscle cell proliferation.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
309-312
DOI
10.4028/www.scientific.net/KEM.342-343.309
Citation
A. S. Zhao, G. C. Li, P. Yang, Y. X. Leng, J. Y. Chen, J. Wang, G. J. Wan, N. Huang, "In Vitro Studies of Macrophage Biological Behavior on Cardiovascular Biomaterials", Key Engineering Materials, Vols. 342-343, pp. 309-312, 2007
Online since
July 2007
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Price
$32.00
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