Paper Title:
Synthesis of Biodegradable Scaffold from Nano Fibers and Evaluation of Protein Adsorption Behaviors on its Surface
  Abstract

The effects of various processing parameters of electro spinning such as concentration, applied voltage, distance from needle to collector on the morphology(especially fiber diameter) of nanofiber matrix was investigated in this study. We found out the concentration of polymer solution was the key parameter to control the fiber diameter. Such a difference on surface morphology of electro spun nanofiber matrix under various processing parameters will show the different behaviors on protein adsorption on the surface contacting with body fluid. Consequently, this results different cell motions on the matrix used on tissue engineering. To evaluate the adsorption of proteins on the surface of sheet type nanofiber matrix, matrix obtained by electro spinning were immersed in FITC labeled proteins solutions. And then, we confirmed adsorption of proteins using laser scanning confocal microscopy (LSCM). The quantitative analysis of adsorbed proteins was also investigated by UV spectroscopy.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
341-344
DOI
10.4028/www.scientific.net/KEM.342-343.341
Citation
J. H. Ko, J. H. Kim, D. J. Chung, "Synthesis of Biodegradable Scaffold from Nano Fibers and Evaluation of Protein Adsorption Behaviors on its Surface ", Key Engineering Materials, Vols. 342-343, pp. 341-344, 2007
Online since
July 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Hong Jie Tang, Juan Juan Guo, Bao Tian Shan, Jin Ren Lu
Abstract:The graft copolymer, chitosan-g-AM-AA, was prepared through graft polymerization of acryamide and acryl acid onto chitosan by...
741
Authors: Xi Li, Jian Zhu, Fu Jian Lv, Jin Guo Wang, Zong Li Xie, Manh Hoang, He Xing Li
Chapter 7: Pollution Control Project (Air, Water, Solid)
Abstract:Two kinds of SnS2 materials were prepared through the hydrothermal route, respectively using thioacetamide (TAA) and thiourea as...
1708
Authors: Qi Xia Liu, Tao Ji, Li Fen He, Qiang Gao
Chapter 2: Materials Science and Engineering
Abstract:Various jute-based activated carbon fibers were prepared by using jute fibers as raw materials, phosphoric acid as activating agent and...
1428
Authors: Yan Jie Bi, Wen Yan Li, Chen Yuan, Bin Song Wang
Chapter 1: Environmental Chemistry, Chemical Manufacturing, Technologies and Engineering
Abstract:In this paper, molecularly imprinted polymers with high selectivity for nonylphenol (NP) were synthesized by sol-gel process using...
55