Paper Title:
The Effects of Chitosan-Tetracycline Membrane on Periodontal Regeneration of One-Wall Intrabony Defects in Beagle Dogs
  Abstract

The aim of this study was to evaluate the regenerative effects of chitosan membranes containing tetracycline (TC) applied to surgically created one-wall intrabony defects in beagle dogs. The defects either received chitosan membrane (CH), chitosan membrane containing 0.5%, 1% TC (CH-TC0.5, CH-TC1.0) or flap operation only. The animals were sacrificed 8 weeks after the experimental surgery, and comparative histological and histometric examinations were done. The amount of junctional epithelium migration and connective tissue adhesion did not show any statistically significant differences among the groups. The amount of new cementum regeneration, and new bone regeneration were significantly greater in CH-TC1.0 group than the control (P<0.05). The results suggest that chitosan membrane combined with 1.0% TC may have beneficial effect on the regeneration of bone and cementum in intrabony periodontal defects.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
361-364
DOI
10.4028/www.scientific.net/KEM.342-343.361
Citation
K. H. Han, G. J. Chae, J. Y. Choi, U. W. Jung, Y. K. Lee, S. H. Choi, "The Effects of Chitosan-Tetracycline Membrane on Periodontal Regeneration of One-Wall Intrabony Defects in Beagle Dogs ", Key Engineering Materials, Vols. 342-343, pp. 361-364, 2007
Online since
July 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: J.S. Kim, S.Y. Na, Y.H. Kown, J.B. Park, J.H. Chung, M.I. Cho, Y. Herr
Abstract:The purpose of this study was to examine if the application of titanium-reinforced expanded polytetrafluoroethylene(TR-ePTFE) membrane...
1075
Authors: Sung Koo Kim, Jung Seok Lee, Gyung Joon Chae, Ui Won Jung, Yong Keun Lee, Chong Kwan Kim, Seong Ho Choi
Abstract:This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate chitosan...
393
Authors: C.S. Lim, S.G. Kim, Sung Chul Lim
Abstract:We evaluated the bone healing effect of grafting with synthetic β-tricalcium phosphate (β-TCP; Cerasorb®), bovine-derived hydroxyapatite...
1261
Authors: G.V.O. Fernandes, Monica Calasans-Maia, F.F. Mitri, Vagner Gonçalves Bernardo, Antonella M. Rossi, G.D.S. Almeida, José Mauro Granjeiro
Abstract:Biomaterials for treatment of bone defects have been studied for a long time. Alloplastic materials, mainly hydroxyapatite (HA), are under...
15
Authors: Lan Lei Wang, Ji Hua Li, Yong Tao Xie, Pi Shan Yang, Yun Mao Liao, Gong Ling Guo
Chapter 2: Materials Science and Engineering
Abstract:The aim of the present study is to investigate the efficacy of nanobiphasic calcium phosphate (nanoBCP) bioceramic in the treatment of...
422