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Properties of Sterilized Human Skin Allografts by Gamma-Irradiation

Journal Key Engineering Materials (Volumes 342 - 343)
Volume Advanced Biomaterials VII
Edited by Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages 365-368
DOI 10.4028/www.scientific.net/KEM.342-343.365
Citation Nak Heon Kang et al., 2007, Key Engineering Materials, 342-343, 365
Online since July, 2007
Authors Nak Heon Kang, Jin Young Kim, Jae Hyoung Ahn, Seok Beom Song, Seog Jin Seo, Ji Hwa Chae, Tae Woon Kim, Kwang Won Lee, Jin Kim, Chong Su Cho, Ke Won Kang
Keywords Gamma Irradiation, Human Skin Allograft, Sterilization
Abstract

The most commonly used sterilization method of human skin allografts is ethylene oxide (EO). EO gas, however, can change the biomechanical properties of the grafts and produce toxic residues which are harmful to the recipient. The heating method cannot be applied for sterilization of soft tissues because of damage due to heat. The purpose of this study was to determine whether it is possible to apply gamma-irradiation for sterilization of soft tissues as well as for hard tissues.

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