Optimization of Experimental Conditions for Synthesis of Nanohydroxyapatite/Collagen Composites in Situ |
| Journal |
Key Engineering Materials (Volumes 342 - 343) |
| Volume |
Advanced Biomaterials VII |
| Edited by |
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon |
| Pages |
45-48 |
| DOI |
10.4028/www.scientific.net/KEM.342-343.45 |
| Online since |
July, 2007 |
| Authors |
Xiao Yan Lin,
Xu Dong Li,
Xing Dong Zhang
|
| Keywords |
In Situ Synthesis, Collagen, Composite, Nanohydroxyapatite (HA), Optimisation |
| Abstract |
L9 (34) orthogonal array design was employed to optimize experimental conditions for
the preparation of the composite using in situ synthesis method and to analyze the relationships
between experimental parameters and mechanical property of the composites. Bending strength of
the composite was considered as a target property of the composites. Hydroxyapatite content in the
composite, synthesis temperature and pH were chosen as main parameters. As a result of this study,
bending strength of the composite appeared in peak with the increase of the hydroxyapatite content
of the composites and synthesis pH, while with the increase of temperature, bending strength
decreased. Optimum experimental conditions for the synthesis of the composites with higher
bending strength were determined. The bending strength of the composites was 90 MPa at the
optimal synthesis conditions. |
| Full Paper |
Get the full paper by clicking here
|
| Preview |
Free first page example |
