Paper Title:
Anticoagulation and Drug Release Behavior of Curcumin-Loaded PLGA Films
  Abstract

Three kinds of curcumin-loaded films (3wt%, 5wt%, 8wt%) were prepared using poly(lactic acid-co-glycol acid (PLGA) as the carrier of curcumin, and studied. The result of Fourier transform infrared spectroscopy (FTIR) and X-ray electron spectroscopy (XPS) show that the curcumin is dispersed in the PLGA films. High performance liquid chromatography (HPLC) analysis suggests that the release of curcumin can last 22-43 days. A fewer number of adhered and activated platelets are observed on the curcumin-loaded PLGA films. The activated partial thromboplastin time (APTT) increases for all curcumin-loaded films.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
481-484
DOI
10.4028/www.scientific.net/KEM.342-343.481
Citation
J. J. Tang, J. Wang, C. J. Pan, Y. J. Weng, N. Huang, "Anticoagulation and Drug Release Behavior of Curcumin-Loaded PLGA Films", Key Engineering Materials, Vols. 342-343, pp. 481-484, 2007
Online since
July 2007
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Price
$32.00
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