Paper Title:
Constructing Bone Graft with Calcium Phosphate Ceramics in Different Non-Osseous Tissue
  Abstract

The study is aimed at to explore the construction of bone graft with calcium phosphate ceramics implanted in subcutaneous fat, and provide applying technique for the in vivo bone tissue engineering. Forty-eight calcium phosphate ceramics (Ca-P ceramics) columns with Φ 5×8 mm were prepared, and eight dogs were used in this experiment. Six samples were implanted in each dog. Three in dorsal muscles while the others in subcutaneous fat. The specimens were harvested at 4, 6, 12 and 24 weeks post operation, for gross observation, SPECT and histological studies. The osseous or osteoid tissue formation at different times in the two non-osseous sites was compared and the new bone grafts in subcutaneous fat and intramuscular implantations were evaluated. The results demonstrated that the bone graft could be constructed not only in muscle but also in subcutaneous fat. Compared to that in muscle, constructing bone graft in subcutaneous fat could have brighter prospect to clinical application.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
641-644
DOI
10.4028/www.scientific.net/KEM.342-343.641
Citation
C.Y. Bao, J. F. Yao, H. S. Fan, L.Y. Sun, B. Zhang, X. L. Wang, X. D. Zhang, "Constructing Bone Graft with Calcium Phosphate Ceramics in Different Non-Osseous Tissue", Key Engineering Materials, Vols. 342-343, pp. 641-644, 2007
Online since
July 2007
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Price
$32.00
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