Paper Title:
Evaluation of Acid-Treated Hyaluronic Acid-Based Hydrogelation
  Abstract

Though hyaluronic acid (HA)-based hydrogel has drawn great attention in biomedical society, it’s long molecular weights sometimes have been problematic due to its difficulty in handling. After reduction of its high molecular weight into smaller sizes with various concentrations of hydrogen chloride solutions, its chemical and biological properties have been examined by changes in viscosity, FTIR spectroscopy and gel permeation chromatography as well as cellular interactions. While FTIR analysis indicated maintenance of its original chemical structures, its viscosity has been remarkably reduced and its extent was dependent upon the employment of acid concentrations. After controlling its molecular weight to approximately 100 kDa and coupling of aminopropymethacrylate to the treated HA, we evaluated in vitro cellular interactions and cell proliferations of the HA-poly(ethylene oxide) (PEO) hydrogel.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
745-748
DOI
10.4028/www.scientific.net/KEM.342-343.745
Citation
M. S. Kim, Y. J. Choi, G. W. Kim, I. S. Noh, Y. D. Park, K. B. Lee, I. S. Kim, S. J. Hwang, "Evaluation of Acid-Treated Hyaluronic Acid-Based Hydrogelation", Key Engineering Materials, Vols. 342-343, pp. 745-748, 2007
Online since
July 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Walter Kenji Yoshito, Nildemar A.M. Ferreira, Ana Carolina S. Coutinho Rumbao, Dolores Ribeiro Ricci Lazar, Valter Ussui
Abstract:Titania ceramics have many applications due to its surface properties and, recently, its nanostructured compounds, prepared by hydrothermal...
788
Authors: Guang Hui Zhang, Lin Liang Yin, Sheng Tao Zhang, Xiao Li
Abstract:The adsorption behavior of sulfamethoxazole as inhibitor for mild steel in 3% HCl solution at 298K has been studied by the methods of...
8
Authors: Agnese Stunda, Dmitrijs Jakovlevs, Lasma Poca, Liga Berzina-Cimdina
Abstract:Modification of surface morphology and composition of niobophosphate glass and glass-ceramic in the system...
61
Authors: M. Abdulwahab, A. Kasim, Bello Kamilu Bello, J.O. Gaminana
Chapter 5: Materials Processing
Abstract:The corrosion inhibition of an aqueous extract of bitter leaf on aluminium alloy in 0.5M hydrochloric acid solution at various temperatures...
319
Authors: Nitus Tipsotnaiyana, Lerpong Jarupan, C. Pechyen
II. Biomaterials Science
Abstract:Rice husk is a form of agricultural biomass that provides an abundant silicon dioxides source. This study use rice husk ash as a material to...
218