Paper Title:
Characterization of Hyaluronic Acid-Poly(Ethylene Oxide) Hydrogel Dependent upon Poly(Ethylene Oxide)
  Abstract

Characterization of an hyaluronic acid (HA)-poly(ethylene oxide) (PEO) hydrogel was performed by changing the number of side arms in a PEO molecule. Verification of grafting chemistry and mechanical strength, as well as swelling behaviors and surface morphologies of the HA-PEO hydrogels were analyzed by employing different x-linking molecular weights (MW) of PEO ranging from 1.7 to 5.0 kDa at a fixed low MW HA in the hydrogel network. Methacrylation to the HA successfully obtained via Michael type reaction between the methacrylate arm groups in HA and the thiol end groups in PEO was observed by XPS. Hydrogel formation was markedly dependent upon the numbers of thiol groups in the PEO molecule. Furthermore the lower MW PEO-based HA hydrogel demonstrated stronger mechanical properties but lower water absorption and the smaller pore sizes on its surface and cross section.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
749-752
DOI
10.4028/www.scientific.net/KEM.342-343.749
Citation
M. S. Kim, Y. J. Choi, G. W. Kim, I. S. Noh, Y. D. Park, K. B. Lee, I. S. Kim, S. J. Hwang, G. W. Yoon, "Characterization of Hyaluronic Acid-Poly(Ethylene Oxide) Hydrogel Dependent upon Poly(Ethylene Oxide)", Key Engineering Materials, Vols. 342-343, pp. 749-752, 2007
Online since
July 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Xiao Min Wang, Xu Dong Li, Gui Qiu Zheng, Jian Ming Jiang, Ji Yong Chen, Xing Dong Zhang
Abstract:A composite hydrogel with interpenetrating network structure was prepared via in-situ synthesis of calcium phosphates during the...
1165
Authors: Mi Sook Kim, Yoon Jeong Choi, Gun Woo Kim, In Sup Noh, Yong Doo Park, Kyu Back Lee, In Sook Kim, Soon Jung Hwang
Abstract:In vitro cell behaviors of calvarial osteoblasts (MC3T3) were evaluated by seeding them on both the surface and inside of in situ hyaluronic...
765
Authors: Xu Pin Zhuang, Wen Jian Deng, Bo Wen Cheng
Abstract:Hydrogels donate moisture to dehydrated tissue and absorb some moisture and accepted in wound healing. Polypropylene (PP) SMS nonwovens were...
513
Authors: Xiao Qi Li, Nei Yan Zhang, Yue Guo Shen
Chapter 6: New Materials and Advanced Materials
Abstract:In this study, poly(N,N-diethylacrylamide-co-itaconic acid) (P(DEA-co-IA)) copolymer hydrogels were synthesized by changing the initial...
1239
Authors: Yu Zhang Du, Dai Di Fan, Xiao Xuan Ma, Chen Hui Zhu, Li Jun Zhang
Chapter 8: Biological Chemical and Technology
Abstract:In this paper, the cross-linking injection hydrogel were synthesized by EDC crosslinker and Carboxymethyl chitosan (CMCS)/Human-like collagen...
1114