Paper Title:
Study of Protein Adsorption on Biomaterial Surfaces by SPR
  Abstract

The aim of this study was to set up a SPR sensor and to investigate protein adsorption onto biomaterial surface using it. Methods: The adsorption of human albumin (Alb), fibrinogen (Fib) and immunoglobulin G (IgG) onto polyurethane (PU) H50-50 and Au surface were measured using this SPR sensor. Results: The results of protein adsorption showed that the amount of Alb, Fib and IgG adsorbed on PU (H50-50) are smaller than Au, and on these two material surfaces, the amount sequence of adsorbed protein is: IgG> Fib > Alb. Both the Alb/Fib ratio and Alb/IgG ratio on PU (H50-50) surface are higher than Au. Conclusion: The antithrombogenicity of PU (H50-50) is better than Au.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
825-828
DOI
10.4028/www.scientific.net/KEM.342-343.825
Citation
J. He, X. Y. Lü, Q. Y. Hong, Z. H. Lu, Y. Huang, P. Z. Sun, "Study of Protein Adsorption on Biomaterial Surfaces by SPR", Key Engineering Materials, Vols. 342-343, pp. 825-828, 2007
Online since
July 2007
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Price
$32.00
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