Paper Title:
In Vivo and In Vitro Tendon Engineering
  Abstract

Tendon is an important supportive tissue of human body responsible for normal physical activity. However, tendon damage and defect remain an important factor for causing disability. The rise of tissue engineering technology provides an effective means of tendon reconstruction and repair, which will bring promise for functional recovery. In our center, tendon engineering is one of major research areas. We have performed the in vivo study by using tenocytes and polyglycolic acid fibers to reconstruct and repair tendon defect in hen and porcine models. The results demonstrated the successful regeneration and repair of tendon defects created in different models. In addition, tendon function was also well recovered by generated autologous tendon tissue that possesses strong biomechanical property. Recently, we have also successfully generated tendon tissue in vitro by using static strain device and bioreactors, which could be potentially transplanted as the tendon graft for tendon defect repair.

  Info
Periodical
Key Engineering Materials (Volumes 342-343)
Edited by
Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon
Pages
9-12
DOI
10.4028/www.scientific.net/KEM.342-343.9
Citation
F. Xu, W. Liu, X. Wei, H. Li, D. J. Cao, Y. L. Cao, "In Vivo and In Vitro Tendon Engineering", Key Engineering Materials, Vols. 342-343, pp. 9-12, 2007
Online since
July 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Ting Wu Qin, Shujiang Zhang, Zhi Ming Yang, Xiang Tao Mo, Xiu Qun Li
Abstract:The purpose of this research is to find out the interaction between histological alterations and mechanical properties of engineered tendon...
11
Authors: Ting Wu Qin, Zhi Ming Yang, Kailu Liang, Hui Qi Xie, Xiu Qun Li
19
Authors: N. Satoh, Takafumi Yoshikawa, Kazuhide Miyazaki, Hideki Shigematsu, Y. Ueda, M. Koizumi, Yoshinori Takakura
Abstract:Availability, storage and transportation of engineered bone tissue fabricated in vitro are major practical problems associated with adequate...
1005
Authors: Jae Ho Jeong, Y.M. Moon, S.O. Kim, S.S. Yun, Hong In Shin
Abstract:Despite many outstanding research works on cartilage tissue engineering, actual clinical application is not quite successful because of the...
89
Authors: Maiko Miura, Jun Fukasawa, Yumiko Yasutomi, Haruka Maehashi, Tomokazu Matsuura, Mamoru Aizawa
Abstract:Tissue engineering has been studied as a novel therapeutic technology which replaces organ transplantation. Tissue engineering consists of...
878