Growth of Smooth Muscle Cell and Endothelial Cell on PLGA Film Containing EGCG |
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| Journal | Key Engineering Materials (Volumes 342 - 343) |
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| Volume | Advanced Biomaterials VII |
| Edited by | Young-Ha Kim, Chong-Su Cho, Inn-Kyu Kang, Suk Young Kim and Oh Hyeong Kwon |
| Pages | 93-96 |
| DOI | 10.4028/www.scientific.net/KEM.342-343.93 |
| Citation | Jin Hyun Chung et al., 2007, Key Engineering Materials, 342-343, 93 |
| Online since | July, 2007 |
| Authors | Jin Hyun Chung, Hye Ryeon Lim, Tek Hyung Lee, Mi Hee Lee, Yeon I Woo, Hyun Sook Baek, Seung Jin Lee, Jeong Koo Kim, Jong Chul Park |
| Keywords | Cell Proliferation, Epigallocatechin 3-O-Gallate, Human Umbilical Vein Endothelial Cell, Poly(DL-Lactic-Co-Glycolic Acid), Smooth Muscle Cells |
| Abstract | Poly (D,L-latic-co-glycolic acid) (PLGA) has been used as the artificial scaffold for blood vessel formation. In order to hinder smooth muscle cell (SMC) angiogenesis, new scaffold design method of loading Epigallocatechin 3-O-gallate (EGCG) on PLGA film was introduced. PLGA and EGCG were dissolved in acetone and film-shape scaffold was manufactured. Antiangiogenetic effect of EGCG released on scaffold was analyzed for SMC and human umbilical vein endothelial cell (HUVEC) and method for selective inhibition from the difference of growth of SMC and HUVEC was suggested. |
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