Paper Title:
Microscopic Multi-Directional Permeability Coefficient of Human Lumbar Vertebral Cancellous Bone Tissue
  Abstract

The mechanical performance of cancellous bone is characterized using experimental measure of parameters (elastic moduli, permeability, etc.) which apply poroelasticity theory. Poroelastic investigations of bone are being extended to investigations of micro-mechanisms of remodeling processes and transport of metabolic product in bone. To understand physiological and pathological behavior of human skeletal system, the accurate measurement of biomechanical properties for bone is the one of important works. Particularly, the microscopic measurement is very important since the biomechanical behavior at the small scale of bone could be closely related to the remodeling of bone. But microscopic measurement of permeability coefficient which is one of important parameter of poroelasticity theory was never measured. In this study, a small scale permeability testing machine was developed to measure accurate coefficient of microscopic specimen permeability. Total of twenty one cylindrical cancellous specimens with a diameter of 500  from seven fresh male and female lumbar vertebrae (14, 39, 59, 61, 69, 75, and 77 years) were fabricated using a micro-milling machine having a resolution of 10 . To determine the directional permeability, bone coordinate was set to be x1 (longitudinal axis) and others were set as x2 (posteroanterior axis) and x3 (latero-medial axis). The measured mean permeability (± SD) values of each direction from x1 to x3 were 9 5.56 10− × (S.D. ± 10 7.10 10− × ), 9 6.66 10− × (S.D. ± 10 6.56 10− × ), and 9 7.04 10− × (S.D. ± 10 8.47 10− × ) m2/Pa/sec, respectively. Mean value in the x1 direction of specimens were the smallest (p<0.01) in comparison to x2 and x3 directions.

  Info
Periodical
Key Engineering Materials (Volumes 345-346)
Edited by
S.W. Nam, Y.W. Chang, S.B. Lee and N.J. Kim
Pages
1161-1164
DOI
10.4028/www.scientific.net/KEM.345-346.1161
Citation
J. H. Hong, Y. H. Park, "Microscopic Multi-Directional Permeability Coefficient of Human Lumbar Vertebral Cancellous Bone Tissue ", Key Engineering Materials, Vols. 345-346, pp. 1161-1164, 2007
Online since
August 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Fumio Nogata
Abstract:We have proposed a new technique for visualising trabecular architecture of spongy bone using ultrasound A-mode signals from a transducer of...
99
Authors: Jung Hwa Hong, Young Hwan Park, Sang Ok Ko, Soon Hyuck Lee, Gon Khang
Abstract:In this study, a minimally invasive assessment using bone strain generated potential (SGP) was developed to examine the amount of...
1082
Authors: Jung Hwa Hong, Young Hwan Park, Sang Ok Ko
Abstract:Osseointegration (OI) could be described as the modality for stable fixation of titanium implant to bone structure. The OI has become a...
1173
Authors: Tae Woo Lee, Chang Yong Ko, Dae Gon Woo, Han Sung Kim
Abstract:Several researchers investigated the mechanical characteristics of human trabecular bone using finite element analysis (FEA) based on micro...
41
Authors: Jung Hwa Hong, Sang Ok Ko, Soon Hyuck Lee
Abstract:"Osseo" refers to bone and "integration" refers to how a prosthesis can be integrated with the bone in residual limbs both arms and legs....
1569