Various asphalt pavement distresses, such as longitudinal cracking, thermal (transverse) cracking, and reflective cracking, are directly related to the fracture properties of the asphalt materials used in the pavement layers. The fracture resistance of asphalt materials significantly influences the service life of asphalt pavements and consequently affects the maintenance and rehabilitation costs of the pavement network. Therefore, there is significant interest in understanding the mechanism of fracture in asphalt pavements and in developing analysis tools that would lead to the selection of asphalt materials with increased fracture resistance. This paper reports a research effort of dynamic observation of the micro-fracture process of asphalt mixture under uniaxial compressed condition by using CT (computerized tomography) method. CT images were analyzed to investigate the process of micro-fracture of asphalt concrete. Research results show that the abnormal belt of density damage of asphalt concrete is the initiation belt of cracking and the turning point in the curve of stress and density distress increment is the point of cracking failure of asphalt concrete.