Laser shock processing (LSP) employs high-energy laser pulses from a solid-state laser system to create intense shock waves into a material, which can induce compressive residual stresses in the target surface and improve its mechanical property efficiency. Residual stress of Ti6Al4V alloy both before and after LSP with multishocks was analysised. The depth of compressive residual stress was found to have a dependence on the number of shocking layers and a slight dependence on the level of irradiance. Surface stress improvements of more than 50% increases are possible after laser shock processing with either large spot or small spot patterns. The large spot gave a surface stress of 432MPa and a depth of over 1mm. The low intensity small spot gave a surface stress of 285MPa with a depth comparable to the large spot. Laser shock processing induces a compressive residual stress field, which increases fatigue crack initiation life and reduces fatigue crack growth rate.