The fracture behavior of brittle materials under different stress ratio has been investigated by means of numerical simulation method with software RFPA2D (Realistic Failure Process Analysis). The fracture dependence of brittle material on biaxial plane stress state was confirmed. The results show that the critical stress intensity factor under biaxial stress increases with the increase of biaxial stress ratio. The simulation tests reveal that the biaxial stresses have strong influence on the fracture properties of glass. The results confirmed that the strain criterion of fracture is feasible while brittle materials under complex stress state.