Paper Title:
Calcium Phosphate Powder for Cancer Vaccination
  Abstract

Cancer cells synthesize abnormal proteins and peptides which are associated to heat shock proteins being overproduced by these cells due to the stress induced by the particular biology of cancer tissue. We have purified on hydroxylapatite powder heat shock proteins using the HAparticles as purification bed, vectors for the proteins and vaccination adjuvant. The powder make possible that the purified HSPs and their associated peptides are transfected to the antigen presenting cells and presented to the T cells for the destruction of the cancer cells bearing the antigens.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
1207-1210
DOI
10.4028/www.scientific.net/KEM.361-363.1207
Citation
P. Frayssinet, D. Ciocca, N. Rouquet, "Calcium Phosphate Powder for Cancer Vaccination", Key Engineering Materials, Vols. 361-363, pp. 1207-1210, 2008
Online since
November 2007
Export
Price
$32.00
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