Paper Title:
Impact of Calcium Phosphate Particle Morphology on Osteoconduction: an In Vivo Study
  Abstract

Apatite/β−TCP particles exhibiting non-conventional urchin-like morphology were prepared by hydrothermal synthesis. Their implantation in the rat calvarium was followed during 60 days. A total absence of osteoconduction was observed despite a favorable chemical composition, stressing the fundamental role of particle morphology on bone regeneration. Results are discussed in relation with other literature data. Possible explanations include the disfavored accumulation of biological mediators due to the acicular shape of the particles and/or a limited accessibility for cells.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
1237-1240
DOI
10.4028/www.scientific.net/KEM.361-363.1237
Citation
C. Drouet, R. Barré, G. Brunel, G. Dechambre, E. Benqué, C. Combes, C. Rey, "Impact of Calcium Phosphate Particle Morphology on Osteoconduction: an In Vivo Study", Key Engineering Materials, Vols. 361-363, pp. 1237-1240, 2008
Online since
November 2007
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Price
$32.00
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