Paper Title:
Human Dentin Transplantation for Bone Engineering
  Abstract

The aims of this study are to confirm the capacity of hard tissue induction by human demineralized dentin matrics (DDM) and calcified dentin matrics (CDM) in subcutaneous tissues of nude mice, and to report a human pioneering trial following the autotransplantation of DDM for bone augmentation in a case of the atrophied upper jaw. Human DDM and CDM particles were prepared from adult, extracted vital teeth, and were implanted into the subcutaneous tissues of 4-week-old nude mice. DDM induced bone and cartilage independently at 4 weeks after implantation, while CDM did not induce a hard tissue formation. Autogenous DDM prepared from the non-functional second molar of a 58-year-old female were grafted on the atrophied jaw and received to the host. Human dentin can be recycled as autogenous biomaterials for local bone engineering.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
1327-1330
DOI
10.4028/www.scientific.net/KEM.361-363.1327
Citation
M. Murata, J. Hino, T. Akazawa, K. Ito, Y. Hirose, M. Ochi, M. Arisue, "Human Dentin Transplantation for Bone Engineering", Key Engineering Materials, Vols. 361-363, pp. 1327-1330, 2008
Online since
November 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Cristian Adrian Raţiu, Simona Cavalu, V. Miclaus, C. Ober, I. Ratiu, O. Ponta
Abstract:The materials used for major sinus lift varies from autogenous or allogenous bone, to animal origin (xenograft) bone or synthetic ...
609
Authors: Junichi Tazaki, Masaru Murata, Y. Nakanishi, M. Ochi, Y. Hirose, T. Akazawa, S. Yodogawa, J. Hino, K. Ito, H. Kitajo, M. Arisue, T. Shibata
Abstract:In our previous clinical study, autogenous demineralized dentin matrices (DDM) prepared from the functional vital teeth (#38, #41) of...
426
Authors: Masaru Murata, Toshiyuki Akazawa, Md. Arafat Kabir, Yasuhito Minamida, M. Shakya, H. Nagayasu, K. Yamada, Manabu Ito, Michiko Sakamoto, Toshio Matsumoto, Takehiko Nakajima
Chapter 3: Bioceramics in Practice of Scaffolds, Tissue Engineering and Implantation
Abstract:Bio-absorbable materials have been strongly needed in bone regenerative surgery. β-TCP ceramics have been widely used as bone tissue scaffold...
187
Authors: Horia Octavian Manolea, Monica Crăițoiu, Eduard Ciucă, Adrian Fronie, Radu Rîcă, Florian Obădan
Chapter 4: Practice of Preclinical Studies of Materials and Technologies
Abstract:Bone graft substitute materials play an important role in oral rehabilitation and understanding the biological effects of these materials is...
222