Paper Title:
Preparation of Porous Synthetic Nanostructured HA Scaffold
  Abstract

The low temperature macro and micro porous hydroxyapatite scaffold was synthesized. The synthetic nanostructured HA powder was prepared by the reaction of Ca(OH)2 and H3PO4. The ultrasound apparatus was used for the separation of the particles during the precipitation process. Hydrogen peroxide (H2O2) was used as a foaming agent. The samples were dried for 3 hours at 120°C. HA (hydroxyapatite) granules exhibited interconnected macro and micro porosity with the micro pore size in the order of 0.01 'm. The specific surface area of the precipitate reached the average value 64.8 ± 11.9 [m2.g-1]. The compressive strength of the low temperature porous HA scaffold granule was very similar to deproteinized bovine bone and other calcium phosphate ceramic materials used in bone regeneration and prepared by high temperature processes. The porosity of the scaffolds 50-75% was determined by mercury porosimetry. In-vitro cytotoxicity test proved the granules to be non toxic.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
211-214
DOI
10.4028/www.scientific.net/KEM.361-363.211
Citation
M. Strnadová, J. Protivinsky, J. Strnad, Z. Vejsicka, "Preparation of Porous Synthetic Nanostructured HA Scaffold", Key Engineering Materials, Vols. 361-363, pp. 211-214, 2008
Online since
November 2007
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Price
$32.00
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