Paper Title:
Bioresorbable Phosphate Scaffolds for Bone Regeneration
  Abstract

In this work, a new bioresorbable phosphate glass (I-CEL2) was prepared in order to use it for the production of 3D-bioresorbable scaffold for bone regeneration. I-CEL2 was characterized to assess its thermal characteristics as well as its bioresorption rate in different medium such as distilled water, Tris-HCl and Simulated Body Fluid (SBF). 3D-macroporous scaffolds were prepared by mixing and pressing I-CEL2 powders and an organic phase and by treating the compact of powders at 550°C for 3 hours. The obtained scaffolds showed a very high porosity and a high resorption rate and are thus suitable candidates for a scaffold to be used as a temporary guide for bone regeneration. The initial response of human marrow stromal cells (hMSCs) has been tested on I-CEL2 surface to describe its biological potential.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
241-244
DOI
10.4028/www.scientific.net/KEM.361-363.241
Citation
C. Vitale-Brovarone, E. Verné, F. Baino, G. Ciapetti, E. Leonardi, N. Baldini, "Bioresorbable Phosphate Scaffolds for Bone Regeneration", Key Engineering Materials, Vols. 361-363, pp. 241-244, 2008
Online since
November 2007
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Price
$32.00
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