The Effect of Reaction Conditions on Hydroxyapatite Particle Morphology and Applications to the Reticulated Foam Method of Scaffold Production |
| Journal |
Key Engineering Materials (Volumes 361 - 363) |
| Volume |
Bioceramics 20 |
| Edited by |
Guy Daculsi and Pierre Layrolle |
| Pages |
3-6 |
| DOI |
10.4028/www.scientific.net/KEM.361-363.3 |
| Online since |
November, 2007 |
| Authors |
J.H. Robinson,
Serena M. Best,
Z. Ahmad,
Mohan J. Edirisinghe
|
| Keywords |
Calcium Phosphate Ceramic, Scaffold |
| Abstract |
The production of nano-scale hydroxyapatite (HA) suspensions to be used for the
reticulated foam method of scaffold production was investigated at temperatures of between 10 and
60OC. An increase in reaction temperature was associated with an increase in the particle size and
some decrease in the aspect ratio of the particles. Pre-treatment of the polyurethane foam template
using PPDS (potassium peroxodisulfate) solution resulted in a significantly improved coating of
HA when compared to the untreated samples or those treated with ethanol. Initial trials coating the
polyurethane with HA produced at the different reaction temperatures showed a superior coating
with the suspension produced at 10OC compared to that at 60OC. A scaffold was produced using the
HA suspension produced at room temperature, but further understanding of the suspension
properties and the optimum conditions for coating of the PU foam are required for improved
mechanical performance. |
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