Radiopaque Strategy for Bone Injectable Substitute |
| Journal |
Key Engineering Materials (Volumes 361 - 363) |
| Volume |
Bioceramics 20 |
| Edited by |
Guy Daculsi and Pierre Layrolle |
| Pages |
39-42 |
| DOI |
10.4028/www.scientific.net/KEM.361-363.39 |
| Online since |
November, 2007 |
| Authors |
Serge Baroth,
Xavier Bourges,
Borhane H. Fellah,
Guy Daculsi
|
| Keywords |
Biphasic Calcium Phosphate, Bone Ingrowth, Radiopaque, Round Granules |
| Abstract |
The purpose of this study ass to investigate the addition of round 80-200m granules
shape radiopaque agents (RA) to synthetic Injectable Bone Substitute to improve contrast
performance for minimal invasive surgery MIS. Composites were obtained by mixing BaSO4, Bi2O3,
Lu2O3 or GdPO4 with calcium deficient apatite CDA which decompose during sintering process in
BCP (60% HA, 40% β-TCP). Each composite was characterized: by XRD, FTIR. Biocompatibility
was tested in vitro and in vivo in bony site (3 weeks implantation in rats). Primary results show that
the suitable radiopaque BCP/RA composite (radiopacity intensity, biological responses) appeared to
be BCP/Ba. Next works will complete the current studies on biological performance in association
with different kind of resorbable injectable bone substitute as suspension, gel or calcium phosphate
cements. |
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