Paper Title:
Calcium Phosphate Mineralized GBR Membranes: Preparation and Properties
  Abstract

The osteoconductive property of calcium phosphate (CaP) biomaterials allow attachment, proliferation, migration, and phenotypic expression of bone cells leading to formation of new bone. The purpose of research is to develop new method of mineralizing commercial GBR membranes with calcium phosphate (CaP) and determine cell response. Resolut Adapt LT (Gore-tex) composed of co-polymer PGA/TMC and Biomend Extend (Zimmer) composed of bovine collagen were used. Membranes were mineralized with CaP using precipitation and new microwave methods. The mineralized and non-mineralized membranes were characterized using SEM, EDS, XRD, FT-IR, and TGA. Cell response to mineralized and non-mineralized membranes was determined using human osteoblastlike cells (MG-63). Microwave method was more efficient in terms of amount of minerals incorporated with membranes and time required. SEM, EDS, and FT-IR identified carbonate apatite in the mineralized membranes. No significant difference in cell proliferation was observed between mineralized and non-mineralized membranes. Greater production of type 1 collagen was observed with CaP mineralized membranes.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
435-438
DOI
10.4028/www.scientific.net/KEM.361-363.435
Citation
A.H.K. Chou, R. Z. LeGeros, D. Q. Mijares, C. Frondoza, J. P. LeGeros, "Calcium Phosphate Mineralized GBR Membranes: Preparation and Properties", Key Engineering Materials, Vols. 361-363, pp. 435-438, 2008
Online since
November 2007
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$32.00
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