Paper Title:
PL DLLA Calcium Phosphate Composite Combined with MBCP Gel® for New Surgical Technologies: Resorbable Osteosynthesis and Bone Substitute
  Abstract

We have performed and evaluated a composite combining PL DLLA and PCa able to have a better control of the hydrolysis and maintain of the mechanical property on time, until wound healing was achieved. Bioabsorbable osteoconductive composite is devoted to the development of resorbable osteosynthesis for spine and osteoarticular surgeries. Such resorbable osteosynthesis will be associated to new bone substitute having high osteogenic property but without initial mechanical property. The purpose of this study was to evaluate the resorption kinetic of a composite using PL DLLA (Poly [L-Lactide-co-D,L-Lactide] acide) charged with PCa granules and the interaction with injectable bioceramic without self hardening. MBCP gel® is a composite associating a mineral phase of an intimate nanoscale melting of hydroxyapatite and beta tri calcium phosphate and an aqueous phase containing a synthetic polymer derived from cellulose HPMC (hydroxyl propyl methyl cellulose).

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
571-574
DOI
10.4028/www.scientific.net/KEM.361-363.571
Citation
G. Jouan, E. Goyenvalle, E. Aguado, R. Cognet, F. Moreau, X. Bourges, G. Daculsi, "PL DLLA Calcium Phosphate Composite Combined with MBCP Gel® for New Surgical Technologies: Resorbable Osteosynthesis and Bone Substitute", Key Engineering Materials, Vols. 361-363, pp. 571-574, 2008
Online since
November 2007
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Price
$32.00
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