Paper Title:
Surface Functionalization of Biomaterials with Alkaline Phosphatase
  Abstract

Two different glasses, one biocompatible but with a low bioactivity index (G1) and the other with an higher bioactivity index (G2), the ceramic version of the second glass and a titanium alloy (Ti6Al4V) have been functionalizated by anchoring alkaline phosphatase (ALP) on their surfaces. The enzyme has been chosen because it is involved in mineralization processes of hard tissues and is a model for more complex ones. ALP has been grafted on glasses and glass-ceramics surfaces both with and without samples silanization and on metallic surfaces with and without tresyl chloride activation. Samples have been analyzed at each step of the functionalization process in order to verify it.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
593-596
DOI
10.4028/www.scientific.net/KEM.361-363.593
Citation
E. Verné, S. Ferraris, C. Vitale-Brovarone, S. Spriano, C. L. Bianchi, M. Morra, C. Cassinelli, "Surface Functionalization of Biomaterials with Alkaline Phosphatase", Key Engineering Materials, Vols. 361-363, pp. 593-596, 2008
Online since
November 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Xia Lu, Li Ang Xing, Pei Zhi Wang, Jun Fu
Abstract:The aim of this study is to fabricate an implant framework for tissue engineering by sintering titanium beads and coating with...
613
Authors: Lise de Jonge, Jeroen J.J.P. van den Beucken, Sander C.G. Leeuwenburgh, Joop G.C. Wolke, John A. Jansen
Abstract:Protein thin films were prepared by electrostatic spray deposition (ESD) from aqueous solutions of the enzyme alkaline phosphatase (ALP)....
589
Authors: En Wei Zhang, Yan Bo Wang, Fei Gao, Shi Cheng Wei, Yu Feng Zheng
Abstract:Two new modified sandblasted and acid etched (SLA) surface methods had been used on commercially pure Ti (Cp-Ti) surface. Scanning electron...
393
Authors: Chi Deng, Bao Wang, Cheng Dong Zhang, Wei Zhi, Jie Weng
Chapter 2: Biochemical Materials, Environmental Materials and Chemistry Processing
Abstract:Aim of the study is to investigate the in vitro reaction between rat bone cell and poly (vinyl alcohol) (PVA)-matrix composites. Sample of...
296
Authors: Alina Sionkowska, Beata Kaczmarek, J. Stalinska, A.M. Osyczka
VI. Composite Materials
Abstract:The properties of new materials based on the blends of collagen and chitosan were studied along with their biological compatibility....
205