Paper Title:

Electrosprayed Nanoapatite: A New Generation of Bioactive Material

Periodical Key Engineering Materials (Volumes 361 - 363)
Main Theme Bioceramics 20
Edited by Guy Daculsi and Pierre Layrolle
Pages 597-600
DOI 10.4028/www.scientific.net/KEM.361-363.597
Citation E.S. Thian et al., 2007, Key Engineering Materials, 361-363, 597
Online since November, 2007
Authors E.S. Thian, Z. Ahmad, Jie Huang, Mohan J. Edirisinghe, S.N. Jayasinghe, D.C. Ireland, Roger A. Brooks, Neil Rushton, William Bonfield, Serena Best
Keywords Carbonate, Electrohydrodynamic Atomisation, Nanoapatite, Osteoblast, Silicon
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Abstract

Fine nanoapatite relics were deposited on glass substrates by electrohydrodynamic atomisation, using nanohydroxyapatite (nHA), nano-carbonated hydroxyapatite (nCHA) and nanosilicon- substituted hydroxyapatite (nSiHA) suspensions. These electrosprayed nanoapatites were evaluated in-vitro using simulated body fluid (SBF) and human osteoblast (HOB) cells. The SBF study revealed that newly-formed apatite layers were observed on the surface of the relics. Furthermore, enhanced HOB cell growth was observed on each of the nanoapatites at all time points. Hence, this work demonstrated that electrosprayed nanoapatites offer considerable potential as biomaterials.