Paper Title:
Calcium Phosphate Coated Rapid Prototyped Porous Titanium Scaffolds
  Abstract

Porous Titanium Scaffolds were produced by using a rapid prototyping technique. These scaffolds were either coated or not with a calcium phosphate coating via an eletrodeposition method. Rat bone marrow mesenchymal stem cells were cultured on the scaffolds at a density of 106 cells/scaffold for a period of 3 days. Cell proliferation was measured by using the Alamar Blue assay. The scaffolds were observed by SEM and polarized light microscopy. Constructs were then implanted subcutaneously for 4 weeks in syngenic rats. Cells proliferated well after seeding. After subcutaneous implantation, histology and SEM revealed the presence of uniform coatings as well as Ca and P deposits in the non-coated scaffolds suggesting mineralization.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
907-910
DOI
10.4028/www.scientific.net/KEM.361-363.907
Citation
M. A. Lopez-Heredia, B. H. Fellah, P. Pilet, C. Leroux, M. Dorget, P. Weiss, J. Sohier, P. Layrolle, "Calcium Phosphate Coated Rapid Prototyped Porous Titanium Scaffolds", Key Engineering Materials, Vols. 361-363, pp. 907-910, 2008
Online since
November 2007
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Price
$32.00
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