Paper Title:
Strontium Activated Bioactive Cellulose Scaffolds
  Abstract

Knits made of cellulose are promising scaffolds for bone tissue engineering applications due to their multi-scale interconnected porosity, biocompatibility and adjustable biodegradability. The approach of this study combines the modification of cellulose with strontium to generate scaffolds capable of forming bone like apatite during exposure to physiological solutions and the release of strontium as an active agent, that might encourage the development of new bone tissue. The Sr-release kinetics during static exposure to simulated body fluid is dominated by an accelerated Sr-release in the initial state followed by a reduced release corresponding to a diffusion controlled rate. Microstructural analyses indicate that initially precipitated SrCO3 transforms to SrxCa1-xCO3 solid solutions that subsequently serve as a template for the precipitation of bone like carbonated hydroxyapatite.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
955-958
DOI
10.4028/www.scientific.net/KEM.361-363.955
Citation
H. Brandt, P. Greil, F. A. Müller, "Strontium Activated Bioactive Cellulose Scaffolds", Key Engineering Materials, Vols. 361-363, pp. 955-958, 2008
Online since
November 2007
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Rungsarit Koonawoot, Cherdsak Saelee, Sakdiphon Thiansem, Sittiporn Punyanitya
Abstract:Hydroxyapatite (HA) is widely used in bioceramic materials for bone grafting. HA scaffolds were synthesized using solid-state reaction...
12