Paper Title:
Synthesis and Characterization of Silica-Chitosan Porous Hybrids for Tissue Engineering
  Abstract

A variety of types of organic polymers have been employed in the synthesis of hybrids with silica. In this work the sol-gel method was used for preparation of macroporous 3D hybrid scaffolds based on silica and chitosan in various compositions (10, 20 and 30% wt). The hybrids were analyzed by Scanning Electron Microscopy (SEM), X-ray Diffraction (DRX) and Infra-red Spectroscopy (FTIR) and the effect of addition of the polymer was evaluated. The foams obtained by sol-gel process were appropriate to produce hybrids based on chitosan-silica and showed large pore size distribution and porosity, except for hybrids with higher polymer content. The FTIR spectroscopy showed a band relative to Si-O-C bond that was also found to increase with the increasing the amounts of chitosan in the hybrid. This fact can suggest an interaction between the organic-inorganic phases in the material and provide new insights on the advantages of chitosansilica hybrid materials produced via sol-gel methodology.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
967-970
DOI
10.4028/www.scientific.net/KEM.361-363.967
Citation
E. M. Reis, W. L. Vasconcelos, H. S. Mansur, M. Pereira, "Synthesis and Characterization of Silica-Chitosan Porous Hybrids for Tissue Engineering", Key Engineering Materials, Vols. 361-363, pp. 967-970, 2008
Online since
November 2007
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$32.00
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