Paper Title:
The Osteogenic Behaviour of Silicon Substituted Hydroxyapatite
  Abstract

Dense and porous HA and Si-HA discs and granules with varying percentages of silicon substitution have been produced and physically and chemically characterised using scanning electron microscopy, surface area analysis, porosimetry, density measurement, image analysis, Xray diffraction, X-ray fluorescence, FT-infrared spectroscopy and in-vitro and in-vivo testing. Results have shown that cell adhesion in-vitro and bone apposition in-vivo are enhanced by the presence of silicon substitution in the hydroxyapatite structure. The biological response to the materials appears to indicate an optimum outcome for levels of silicon substitution of 0.8wt%.

  Info
Periodical
Key Engineering Materials (Volumes 361-363)
Main Theme
Edited by
Guy Daculsi and Pierre Layrolle
Pages
985-988
DOI
10.4028/www.scientific.net/KEM.361-363.985
Citation
S. Best, S. Zou, R. A. Brooks, J. Huang, N. Rushton, W. Bonfield, "The Osteogenic Behaviour of Silicon Substituted Hydroxyapatite", Key Engineering Materials, Vols. 361-363, pp. 985-988, 2008
Online since
November 2007
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$32.00
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