In order to do the precision grinding of optical aspheric lens, it is essential to achieve high quality surface roughness. Experiments show that the contacting area between the wheel and workpiece in a grinding process is critical to influence the surface roughness for a fine grit size resin bonded wheel. The precision grinding are performed with BK7 optical lens. This paper deals with the grinding of an aspheric surface optical lens by diamond wheel. This study also compares each machining parameter (work spindle speed, wheel spindle speed, feedrate, etc.) in rough grinding, fine grinding and polishing on the aspheric lens. In this study, several experiments were carried out BK7 optical glass lens by using vitrified, metal, resin bond diamond wheel and the polisher of urethane ball was used to remove the tool marks with an ultra-precision in-line grinding system. It was found that machining parameters significantly influence the surface roughness of aspheric optical lens.