Paper Title:
Simulation of Bone Remodelling and Bone Ingrowth within Scaffolds
  Abstract

Bone Tissue Engineering is a fast growing interdisciplinary branch of research that aims to find adequate replacements or scaffolds for bone, in order to improve its ability to regenerate itself. The present work summarizes the most relevant functional properties of bone and its ability of adaptation, remarking the most crucial characteristics that these replacements must fulfill for appropriate bone regeneration, including the correct selection of the material and structure. The second part presents current trends in computational modeling of bone remodeling and bone ingrowth within scaffolds, with special emphasis on the description of two different mathematical approaches to model these biological regenerative events. We demonstrate that computational modeling is a useful tool for bone scaffold design that allows considering multiple factors some of them very difficult to evaluate experimentally.

  Info
Periodical
Edited by
Maria Vallet-Regí
Pages
225-273
DOI
10.4028/www.scientific.net/KEM.377.225
Citation
J. A. Sanz-Herrera, J.M. García-Aznar, M. Doblaré, "Simulation of Bone Remodelling and Bone Ingrowth within Scaffolds", Key Engineering Materials, Vol. 377, pp. 225-273, 2008
Online since
March 2008
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: H. Teramoto, A. Kawai, S. Sugihara, A. Yoshida, Hisahiro Inoue
269
Authors: B. Niechoda, M. Gianoutsos, Yong Ning Yu, W.R. Walsh
663
Authors: G.V.O. Fernandes, Monica Calasans-Maia, F.F. Mitri, Vagner Gonçalves Bernardo, Antonella M. Rossi, G.D.S. Almeida, José Mauro Granjeiro
Abstract:Biomaterials for treatment of bone defects have been studied for a long time. Alloplastic materials, mainly hydroxyapatite (HA), are under...
15
Authors: Christine Knabe, Georg Berger, Renate Gildenhaar, Paul Ducheyne, Michael Stiller
Abstract:Although autogenous bone grafts are currently the standard of care for bone reconstruction in implant dentistry, bone substitute materials...
214
Authors: Li Jun Yang, Xi Nan Dang, Li Li Wang, Lian Zhou
Abstract:Modeling, design and fabrication of tissue scaffolds with intricate architecture, porosity and pore size for desired tissue properties...
230