Paper Title:
Comparison of the Chemical Reactivity and Bioactivity of Two Bioactive Glasses 47S6 and 48S4
  Abstract

This work is focused on the bioactive glasses obtained by melting and rapid quenching. Two glasses with mineral composition of: 47% SiO2 - 26% CaO - 21% Na2O - 6% P2O5 and 48% SiO2 - 30% CaO - 18% Na2O - 4% P2O5 were investigated. The aim of this study was to establish the kinetics of HCAp layer formation “in vitro” and to control the adhesion and proliferation cells of the two glasses in contact with osseous cells. Obtained results permit to evaluate their chemical reactivity and their bioactivity after immersion in the SBF-K9. Ionic exchanges between biomaterials and SBF liquid during the “in vitro” experiments highlight the differences of the chemical reactivity and bioactivity of 47S6 and 48S4. The structural basis for the effect of cristallinity on the rates of HCA formation in vitro in favour of glasses was also established. The melt derived 47S6 and 48S4 glasses offer to surgeons new compositions with different bioactivity kinetic that bioglassÒ 45S6 and can be adaptable in some other bony pathology.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
107-110
DOI
10.4028/www.scientific.net/KEM.396-398.107
Citation
H. Oudadesse, M. Mami, R. Dorbez-Sridi, P. Pellen-Mussi, F. Perez, S. Jeanne, D. Chauvel-Lebret, G. Cathelineau, "Comparison of the Chemical Reactivity and Bioactivity of Two Bioactive Glasses 47S6 and 48S4", Key Engineering Materials, Vols. 396-398, pp. 107-110, 2009
Online since
October 2008
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