Paper Title:
In Vivo Evaluation of Porous Titanium Implants with Biomimetic Coating
  Abstract

The osseointegration of porous titanium implants was evaluated in the present work. Implants were fabricated from ASTM grade 2 titanium by a powder metallurgy method. Part of these implants were submitted to chemical and thermal treatment in order to deposit a biomimetic coating, aiming to evaluate its influence on the osseointegration of the implants. The implants were characterized by Scanning Electron Microscopy (SEM), Electron Dispersive X-Ray Spectroscopy (EDS) and Raman Spectroscopy. Three coated and three control (uncoated) implants were surgically inserted into thirty albino rabbits’ left and right tibiae, respectively. Tibiae samples were submitted to histological and histomorphometric analyses, utilizing SEM, optical microscopy and mechanical tests. EDS results indicated calcium (Ca) and phosphorous (P) at the surface and Raman spectra exhibited an intense peak, characteristic of hydroxyapatite (HA). Bone neoformation was detected at the bone-implant interface and inside the pores, including the central ones. The mean bone neoformation percentage in the coated implants was statistically higher at 15 days, compared to 30 and 45 days. The mechanical tests showed that coated implants presented higher resistance to displacement, especially after 30 and 45 days.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
179-182
DOI
10.4028/www.scientific.net/KEM.396-398.179
Citation
A. C. P. Machado, M. V. de Oliveira, R. P. Pereira, Y. R. Carvalho, C. A. A. Cairo, "In Vivo Evaluation of Porous Titanium Implants with Biomimetic Coating", Key Engineering Materials, Vols. 396-398, pp. 179-182, 2009
Online since
October 2008
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Price
$32.00
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