Paper Title:
Study of Morphology of Cardiac Valves (Human and Bovine Pericardium) after In Vivo Calcification
  Abstract

Pathologic calcification can lead to failure or deterioration of cardiac valves. Several researchers have tried alternatives to construct these devices, such as the incorporation or utilization of new biomaterials able to inhibit or decrease the calcification process. In vitro calcification tests can be used to screen new biomaterials regarding their potential to calcify in vivo. However, the mechanisms involved in both cases are not completely understood. In order to collect more information about the calcification process of implanted materials, morphology and elemental analyses of calcified cardiac valve fragments explanted from different patients were investigated and compared to previous reports of in vitro calcification tests. Scanning Electron Microscopy (SEM) and energy dispersive spectroscopy (EDS) analyses indicated that the calcium phosphate deposits from both bovine pericardium and human cardiac valves calcified in vivo were similar to the deposits obtained from in vitro calcification samples as previously reported in the literature.

  Info
Periodical
Key Engineering Materials (Volumes 396-398)
Main Theme
Edited by
Marcelo Prado and Cecília Zavaglia
Pages
191-194
DOI
10.4028/www.scientific.net/KEM.396-398.191
Citation
G. M. Nogueira, C. G. Aimoli, R. F. Weska, A. A. Leirner, M. J.S. Maizato, O. Z. Higa, B. Polakiewicz, R. N.M. Pitombo, M. M. Beppu, "Study of Morphology of Cardiac Valves (Human and Bovine Pericardium) after In Vivo Calcification ", Key Engineering Materials, Vols. 396-398, pp. 191-194, 2009
Online since
October 2008
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$32.00
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